THC-O-phosphate

THC-O-phosphate is a metabolite of THC, the primary psychoactive component of cannabis. It is formed in the body after consumption of THC, and has been investigated for its potential use in drug tests for cannabis use.

Metabolism

When THC is consumed, it is metabolized by the body into several different compounds, one of which is THC-O-phosphate. This metabolite is formed in the liver by the action of the enzyme CYP2C9. The formation of THC-O-phosphate is a key step in the body's process of eliminating THC.

Detection

Because THC-O-phosphate is a metabolite of THC, it can be detected in the body after cannabis use. This has led to its use in drug tests for cannabis. The presence of THC-O-phosphate in the body can be detected for several days after cannabis use, making it a reliable indicator of recent use.

Pharmacology

The pharmacological effects of THC-O-phosphate are not well understood. It is known to be less psychoactive than THC, but it may contribute to the overall effects of cannabis use through its interactions with other cannabinoids and metabolites.

See also

• Cannabinoid
• Drug test
• Metabolite
• Pharmacology

THC-O-phosphate Resources
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