2,5-Dimethoxy-4-fluoroamphetamine

Chemical structure of 2,5-Dimethoxy-4-fluoroamphetamine

2,5-Dimethoxy-4-fluoroamphetamine (DOF) is a psychedelic drug and a substituted amphetamine. It is a member of the 2C family of phenethylamines, which are known for their psychoactive properties. DOF is chemically related to other compounds such as 2,5-dimethoxy-4-bromoamphetamine (DOB) and 2,5-dimethoxy-4-iodoamphetamine (DOI).

Chemical Structure

2,5-Dimethoxy-4-fluoroamphetamine is a phenethylamine derivative, characterized by the presence of methoxy groups at the 2 and 5 positions of the phenyl ring, and a fluorine atom at the 4 position. The chemical formula is C₁₁H₁₆FNO₂.

Pharmacology

DOF acts primarily as a serotonin receptor agonist, particularly at the 5-HT2A receptor, which is believed to be responsible for its psychedelic effects. The compound's activity at other serotonin receptors, such as 5-HT2B and 5-HT2C, may also contribute to its overall pharmacological profile.

Effects

The effects of 2,5-Dimethoxy-4-fluoroamphetamine are similar to those of other psychedelic amphetamines, including altered perception, mood changes, and cognitive shifts. The intensity and duration of these effects can vary depending on the dose and individual sensitivity.

Legal Status

The legal status of DOF varies by country. In some jurisdictions, it may be classified as a controlled substance due to its structural similarity to other regulated psychedelics. Users should be aware of the legal implications of possessing or using this compound in their region.

Related Compounds

• 2,5-Dimethoxy-4-bromoamphetamine (DOB)
• 2,5-Dimethoxy-4-iodoamphetamine (DOI)
• 2,5-Dimethoxy-4-methylamphetamine (DOM)
• 2,5-Dimethoxy-4-ethylamphetamine (DOET)

See Also

• Psychedelic drug
• Phenethylamine
• Serotonin receptor

Related Pages

• Alexander Shulgin
• Psychedelic research
• Amphetamine