JWH-057

From WikiMD's Food, Medicine & Wellness Encyclopedia

JWH-057 is a compound from the naphthoylindole family, which acts as a potent cannabinoid agonist at both the CB1 and CB2 receptors, but with some selectivity for CB2. It is an analgesic drug used in scientific research.

Chemistry[edit | edit source]

JWH-057 belongs to the naphthoylindole family of compounds, named after the scientist John W. Huffman who first synthesized these cannabinoids. It is closely related to other naphthoylindoles such as JWH-018 and JWH-073.

Pharmacology[edit | edit source]

JWH-057 acts as a potent cannabinoid agonist at both the CB1 and CB2 receptors, with some selectivity for CB2. This makes it a full agonist at this receptor, which is involved in the analgesic effects of cannabinoids.

Medical Use[edit | edit source]

As an analgesic, JWH-057 may have potential therapeutic applications for the treatment of pain. However, further research is needed to fully understand its effects and potential medical uses.

Legal Status[edit | edit source]

The legal status of JWH-057 varies by country and is subject to change. It is important to check the current legal status in your jurisdiction before use.

See Also[edit | edit source]

JWH-057 Resources
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Contributors: Prab R. Tumpati, MD