5F-AMB

5F-AMB (also known as 5F-MMB-PINACA and 5F-AMB-PINACA) is a synthetic cannabinoid from the family of indazole-3-carboxamides. It is a potent agonist of the CB1 receptor, and is often used in the research of cannabinoid receptor agonists.

Chemistry

5F-AMB is a synthetic cannabinoid that is structurally related to AB-PINACA, a compound originally developed by Pfizer in the 2000s. The chemical structure of 5F-AMB includes an indazole-3-carboxamide moiety, which is a defining feature of this class of synthetic cannabinoids. The "5F" in the name refers to the fluorine atom attached to the pentyl chain.

Pharmacology

5F-AMB is a potent agonist of the CB1 receptor, with a reported EC50 value of 0.7 nM. This makes it significantly more potent than many other synthetic cannabinoids. The effects of 5F-AMB on the human body can vary widely, depending on the dose and the individual's personal physiology. However, common effects can include relaxation, euphoria, and altered perception.

Legal Status

The legal status of 5F-AMB varies by country. In the United States, it is a Schedule I controlled substance. In the United Kingdom, it is a Class B drug. In Japan, it is designated as a controlled substance under the Pharmaceutical and Medical Device Act.

See Also

• Synthetic cannabinoids
• Indazole
• Cannabinoid receptor

References

5F-AMB Resources
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