CUMYL-PINACA

CUMYL-PINACA is a synthetic cannabinoid that has been identified in illegal products. It is a potent agonist for cannabinoid receptors CB1 and CB2. CUMYL-PINACA was first identified in a smoking mixture in 2016.

Chemistry

CUMYL-PINACA is an indazole-3-carboxamide based synthetic cannabinoid. It is structurally related to other synthetic cannabinoids like 5F-AB-PINACA, 5F-ADB, and AM-2201. The systematic name of CUMYL-PINACA is N-(1-amino-3,3-dimethyl-1-oxobutan-2-yl)-1-(cyclohexylmethyl)-1H-indazole-3-carboxamide.

Pharmacology

CUMYL-PINACA acts as a potent agonist for the CB1 receptor and CB2 receptor, with EC50 values of 0.58 nM and 6.12 nM, respectively. The exact toxicological properties of CUMYL-PINACA are not known.

Legal Status

CUMYL-PINACA is a controlled substance in some countries including Germany and the United States. In the United States, it is a Schedule I controlled substance.

See Also

• Synthetic cannabinoids
• Cannabinoid receptor
• Indazole

References

CUMYL-PINACA Resources
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