25B-NBF
25B-NBF is a psychedelic phenethylamine that is part of the 2C family. It was first synthesized by Alexander Shulgin and documented in his book PiHKAL.
Chemistry[edit | edit source]
25B-NBF is a derivative of the phenethylamine 2C-B, which itself is a derivative of mescaline. The full name of the compound is 2-(4-bromo-2,5-dimethoxyphenyl)-N-[(2-fluorophenyl)methyl]ethanamine. It belongs to the 25-NB family, a group of phenethylamine derivatives that are named for the NBF group attached to the base phenethylamine structure.
Pharmacology[edit | edit source]
The pharmacology of 25B-NBF is not well-studied. However, it is known to act as a potent and selective 5-HT2A receptor agonist, which is thought to be responsible for its psychedelic effects. Like other 2C drugs, 25B-NBF is thought to produce its effects by binding to serotonin receptors in the brain, leading to an altered state of consciousness.
Effects[edit | edit source]
The effects of 25B-NBF can vary greatly depending on the dose, set, and setting. Common effects reported by users include visual hallucinations, enhanced colors, increased body awareness, euphoria, and changes in perception of time. Some users also report experiencing negative effects such as anxiety, paranoia, and uncomfortable body sensations.
Legality[edit | edit source]
25B-NBF is illegal in many countries, including the United States, where it is classified as a Schedule I controlled substance. It is also illegal in the United Kingdom under the Psychoactive Substances Act 2016.
Safety[edit | edit source]
The safety profile of 25B-NBF is largely unknown due to a lack of scientific research. As with all psychedelics, it is recommended that users take precautions such as having a sober sitter present, starting with a low dose, and avoiding mixing with other substances.
See also[edit | edit source]
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Contributors: Prab R. Tumpati, MD