JWH-147

JWH-147

Chemical structure of JWH-147

JWH-147 is a synthetic cannabinoid that acts as a potent agonist at the cannabinoid receptors. It is part of the naphthoylindole family of compounds, which are known for their ability to mimic the effects of tetrahydrocannabinol (THC), the primary psychoactive component of cannabis.

Chemical Properties

JWH-147 is chemically classified as a naphthoylindole, which is a subclass of synthetic cannabinoids. The chemical structure of JWH-147 includes a naphthalene group attached to an indole core, which is a common feature among compounds in this class. The presence of these groups contributes to its high affinity for cannabinoid receptors.

Pharmacology

JWH-147 acts as a full agonist at both the CB1 and CB2 cannabinoid receptors. These receptors are part of the endocannabinoid system, which plays a role in regulating various physiological processes including mood, appetite, and pain sensation. The activation of these receptors by JWH-147 can lead to effects similar to those produced by natural cannabinoids.

Effects and Usage

The effects of JWH-147 are similar to those of other synthetic cannabinoids, including euphoria, altered perception, and relaxation. However, due to its potency, the effects can be more intense and may include adverse reactions such as anxiety, paranoia, and tachycardia. JWH-147 and similar compounds have been used in research to study the endocannabinoid system and the effects of cannabinoid receptor activation.

Legal Status

The legal status of JWH-147 varies by country. In many jurisdictions, it is classified as a controlled substance due to its potential for abuse and lack of accepted medical use. The regulation of synthetic cannabinoids like JWH-147 is part of broader efforts to control the distribution and use of designer drugs.

Related Pages

• Cannabinoid receptor
• Synthetic cannabinoid
• Endocannabinoid system
• Naphthoylindole