JWH-147

JWH-147 is a synthetic cannabinoid from the naphthoylindole family, which acts as a potent cannabinoid agonist at both the CB1 and CB2 receptors, with a Ki of 0.69nM at CB1 and 1.8nM at CB2. It was discovered by and named after Dr. John W. Huffman.

Chemistry

JWH-147 is part of the naphthoylindole family of synthetic cannabinoids. It is a complex molecule with a molecular formula of C25H25NO2. The systematic name for JWH-147 is 1-pentyl-3-(2-methoxyphenylacetyl)indole.

Pharmacology

JWH-147 acts as a potent cannabinoid agonist at both the CB1 and CB2 receptors. The Ki values for this compound are 0.69nM at CB1 and 1.8nM at CB2. This makes it one of the most potent compounds in the JWH series.

Effects

The effects of JWH-147 are similar to those of other cannabinoids. They include relaxation, euphoria, altered perception, and in some cases, hallucinations. However, due to its potency, the effects of JWH-147 can be more intense and longer-lasting than those of natural cannabinoids.

Legal Status

The legal status of JWH-147 varies by country. In some countries, it is classified as a controlled substance, while in others it is legal to possess and use.

See Also

• JWH-018
• JWH-073
• JWH-200
• Cannabinoid
• Cannabinoid receptor

References

JWH-147 Resources
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