JWH-007

JWH-007 is a synthetic cannabinoid found in the naphthoylindole family. It acts as a full agonist at both the CB1 and CB2 cannabinoid receptors, with a binding affinity of 9.00 ± 5.00 nM at CB1 and 2.94 ± 2.65 nM at CB2.

Chemistry

JWH-007 is part of the Naphthoylindole family of synthetic cannabinoids. It is structurally related to other synthetic cannabinoids including JWH-018, JWH-073, and JWH-200.

Pharmacology

JWH-007 acts as a full agonist at both the CB1 and CB2 cannabinoid receptors. Its binding affinity is 9.00 ± 5.00 nM at CB1 and 2.94 ± 2.65 nM at CB2. This makes it one of the most potent compounds in the naphthoylindole series, having a binding affinity at CB1 that is 5 times greater than that of THC, the main active component in cannabis.

Legal Status

In the United States, JWH-007 is a Schedule I controlled substance. It is also illegal in many other countries, including the United Kingdom, where it is a Class B drug under the Misuse of Drugs Act 1971.

See Also

• Cannabinoid receptor
• Synthetic cannabinoids
• Naphthoylindole

References

JWH-007 Resources
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