2CBFly-NBOMe

From WikiMD's Food, Medicine & Wellnesspedia

2CBFly-NBOMe is a novel psychedelic substance of the phenethylamine and NBOMe chemical classes. It is a derivative of the phenethylamine 2C-B-FLY and is reported to produce an array of highly psychedelic effects similar to those of other potent serotonin receptor agonists when administered.

History and culture[edit | edit source]

2CBFly-NBOMe was first synthesized by a team at Purdue University led by David Nichols. It is part of a series of NBOMe compounds that were investigated for their potential use in the treatment of various psychological disorders. However, due to its potent psychedelic effects and lack of research, it is not currently used in any official medical capacity.

Chemistry[edit | edit source]

2CBFly-NBOMe is a compound of the phenethylamine class. Phenethylamines are compounds containing a phenyl ring bound to an amino (NH2) group through an ethyl chain. 2CBFly-NBOMe contains a benzyl substitution at R1. It is a derivative of 2C-B-FLY, which contains a bromine atom attached at carbon R4 of the phenyl ring.

Pharmacology[edit | edit source]

Due to the lack of scientific research regarding the use of 2CBFly-NBOMe, all discussion regarding the pharmacology of this substance is purely based on its structure and subjective effect similarities to other psychedelic phenethylamines such as 2C-B and NBOMe compounds. 2CBFly-NBOMe likely acts as a 5-HT2A partial agonist. The psychedelic effects are believed to come from its efficacy at the 5-HT2A receptors.

Subjective effects[edit | edit source]

The effects of 2CBFly-NBOMe can be broken down into several components which progressively intensify proportional to dosage. These include hallucinations, synesthesia, a sense of time distortion, and ego loss. It is also reported to produce a significant physical energy increase and a unique perspective shift relative to traditional psychedelics.

Toxicity and harm potential[edit | edit source]

As with all research chemicals, long-term health effects and toxicity are not known, as there is no data concerning the carcinogenic, mutagenic, or teratogenic effects of this compound. It is strongly recommended that one use harm reduction practices when using this substance.

Legal status[edit | edit source]

The legal status of 2CBFly-NBOMe varies from country to country. It is illegal in many countries, including the United States, where it is classified as a Schedule I controlled substance.

See also[edit | edit source]

References[edit | edit source]

2CBFly-NBOMe Resources
Doctor showing form.jpg
Wiki.png

Navigation: Wellness - Encyclopedia - Health topics - Disease Index‏‎ - Drugs - World Directory - Gray's Anatomy - Keto diet - Recipes

Search WikiMD


Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro) available.
Advertise on WikiMD

WikiMD is not a substitute for professional medical advice. See full disclaimer.

Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.


Contributors: Prab R. Tumpati, MD