5-Bromo-DMT

5-Bromo-DMT (5-bromo-N,N-dimethyltryptamine) is a psychedelic alkaloid of the tryptamine class. It is found in certain marine invertebrates, notably the sponge Smenospongia aurea and Smenospongia echina. It is structurally related to the more well-known dimethyltryptamine (DMT), differing only by the addition of a bromine atom at the 5 position of the indole ring.

Chemistry

5-Bromo-DMT is a member of the tryptamine class of compounds, which are structurally derived from the essential amino acid tryptophan. The core structure consists of a bicyclic indole heterocycle attached at R3 to a terminal amine group via an ethyl side chain. 5-Bromo-DMT is substituted at R5 of its indole heterocycle with a bromine atom; this is the only point of divergence from its parent compound DMT.

Pharmacology

The pharmacology of 5-Bromo-DMT is not well-studied. However, it is known to act as a serotonin receptor agonist. Like other tryptamines, it is thought to act primarily on the 5-HT2A receptor, which is involved in the cognitive, perceptual, and mood effects of psychedelics.

Effects

The effects of 5-Bromo-DMT are not well-documented due to its rarity and the lack of scientific research. Anecdotal reports suggest that it produces effects similar to other tryptamines, including visual hallucinations, altered thought processes, and changes in mood. However, these reports should be taken with caution due to the lack of controlled studies.

Legal Status

The legal status of 5-Bromo-DMT varies by country. In the United States, it is not specifically listed as a controlled substance, but it could potentially be considered an analog of DMT, which is a Schedule I drug under the Controlled Substances Act.

See Also

• 4-AcO-DMT
• 5-MeO-DMT
• Psilocybin

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