JWH-149
Overview[edit | edit source]
JWH-149 is a synthetic cannabinoid that acts as a potent agonist at the cannabinoid receptors. It is part of the naphthoylindole family of compounds, which are known for their psychoactive effects similar to those of tetrahydrocannabinol (THC), the primary active component of cannabis.
Chemical Structure[edit | edit source]
JWH-149 is chemically classified as a naphthoylindole, which is characterized by a naphthalene group attached to an indole core. The specific structure of JWH-149 includes a 1-pentyl-3-(1-naphthoyl)indole configuration, which contributes to its high affinity for cannabinoid receptors.
Pharmacology[edit | edit source]
JWH-149 acts as a full agonist at both the CB1 and CB2 cannabinoid receptors. These receptors are part of the endocannabinoid system, which plays a role in regulating various physiological processes such as mood, appetite, and pain sensation. The activation of these receptors by JWH-149 can lead to effects similar to those produced by natural cannabinoids.
Effects[edit | edit source]
The effects of JWH-149 are similar to those of other synthetic cannabinoids and can include euphoria, altered perception, and relaxation. However, due to its potency, JWH-149 can also cause adverse effects such as anxiety, paranoia, and tachycardia. The use of synthetic cannabinoids like JWH-149 has been associated with a range of health risks, particularly when used in high doses or in combination with other substances.
Legal Status[edit | edit source]
The legal status of JWH-149 varies by country. In many jurisdictions, it is classified as a controlled substance due to its potential for abuse and lack of accepted medical use. The regulation of synthetic cannabinoids is often part of broader efforts to control new psychoactive substances.
Related Compounds[edit | edit source]
JWH-149 is part of a larger group of synthetic cannabinoids developed by John W. Huffman and his team. Other related compounds include JWH-018, JWH-073, and JWH-250, each with varying affinities and effects on cannabinoid receptors.
See Also[edit | edit source]
Related Pages[edit | edit source]
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates, categories Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
