Salvinorin B ethoxymethyl ether

Salvinorin B ethoxymethyl ether (also known as 2-O-ethoxymethylsalvinorin B) is a semi-synthetic analogue of the natural product salvinorin A, which is found in the psychoactive plant Salvia divinorum. Salvinorin B ethoxymethyl ether is known for its potent psychedelic effects, and is considered one of the most potent kappa opioid receptor agonists.

Chemistry

Salvinorin B ethoxymethyl ether is a semi-synthetic compound derived from salvinorin A. The chemical structure of salvinorin B ethoxymethyl ether includes an ethoxymethyl group attached to the 2-position of the salvinorin A molecule. This modification increases the potency and duration of the compound's effects compared to salvinorin A.

Pharmacology

Salvinorin B ethoxymethyl ether acts as a highly potent and selective kappa opioid receptor agonist. The kappa opioid receptor is a type of G protein-coupled receptor that is involved in the perception of pain, consciousness, and mood. Activation of the kappa opioid receptor by salvinorin B ethoxymethyl ether results in profound alterations in perception and cognition, which are described as psychedelic effects.

Effects

The effects of salvinorin B ethoxymethyl ether are similar to those of other potent kappa opioid receptor agonists. These can include intense hallucinations, altered perception of reality, and changes in mood. The intensity and duration of these effects can vary depending on the dose and route of administration.

Legal Status

The legal status of salvinorin B ethoxymethyl ether varies by country. In some jurisdictions, it is considered a controlled substance due to its psychoactive properties. However, in other areas, it may be legal to possess and use.

See Also

• Salvinorin A
• Salvia divinorum
• Kappa opioid receptor
• Psychedelic drug