Salvinorin B methoxymethyl ether

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Salvinorin B methoxymethyl ether (also known as 2-O-methoxymethylsalvinorin B) is a semi-synthetic derivative of the natural product salvinorin A, which is found in the plant Salvia divinorum. It is a potent and selective kappa opioid receptor agonist, and its effects are thought to be mediated primarily through this mechanism.

Chemistry[edit | edit source]

Salvinorin B methoxymethyl ether is a semi-synthetic compound, meaning it is not found in nature but is derived from a natural product. It is made by modifying the structure of salvinorin A, a compound found in the plant Salvia divinorum. The modification involves the addition of a methoxymethyl group to the 2-position of the salvinorin A molecule.

Pharmacology[edit | edit source]

Salvinorin B methoxymethyl ether is a potent and selective kappa opioid receptor agonist. This means it binds to and activates the kappa opioid receptor, a type of protein found on the surface of certain cells in the brain and spinal cord. Activation of the kappa opioid receptor is thought to be responsible for the compound's psychoactive effects.

Effects[edit | edit source]

The effects of Salvinorin B methoxymethyl ether are similar to those of other kappa opioid receptor agonists. These can include hallucinations, changes in perception, and altered states of consciousness. However, the specific effects can vary greatly depending on the dose and individual user.

Legal Status[edit | edit source]

The legal status of Salvinorin B methoxymethyl ether varies by country and region. In some places, it is regulated under laws pertaining to salvinorin A and Salvia divinorum. In others, it may be legal to possess and use.

See Also[edit | edit source]

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Contributors: Prab R. Tumpati, MD