CUMYL-THPINACA

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Synthetic cannabinoid


CUMYL-THPINACA
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CUMYL-THPINACA is a synthetic cannabinoid that has been used in scientific research and is often found in synthetic cannabis products. It is known for its potent agonistic activity at the cannabinoid receptors.

Chemical structure and properties[edit | edit source]

CUMYL-THPINACA is classified as an indazole-based synthetic cannabinoid. Its chemical structure includes a cumyl group attached to an indazole core, with a pentyl side chain. This structure is similar to other synthetic cannabinoids, which are designed to mimic the effects of tetrahydrocannabinol (THC), the active component of cannabis.

Pharmacology[edit | edit source]

CUMYL-THPINACA acts as a potent agonist at the CB1 and CB2 cannabinoid receptors. These receptors are part of the endocannabinoid system, which plays a role in regulating various physiological processes such as mood, memory, and pain sensation. The activation of these receptors by CUMYL-THPINACA can lead to psychoactive effects similar to those of THC.

Usage and effects[edit | edit source]

Synthetic cannabinoids like CUMYL-THPINACA are often sprayed onto plant material and sold as "herbal incense" or "spice." Users may experience effects such as euphoria, altered perception, and relaxation. However, these substances can also cause adverse effects, including anxiety, paranoia, and in some cases, severe health complications.

Legal status[edit | edit source]

The legal status of CUMYL-THPINACA varies by country. In many jurisdictions, it is classified as a controlled substance due to its potential for abuse and lack of accepted medical use. Regulatory agencies continue to monitor and update the legal status of synthetic cannabinoids as new compounds are developed and identified.

Health risks[edit | edit source]

The use of CUMYL-THPINACA and other synthetic cannabinoids has been associated with numerous health risks. These include cardiovascular problems, seizures, and acute kidney injury. The variability in potency and composition of synthetic cannabinoid products increases the risk of overdose and adverse reactions.

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Contributors: Prab R. Tumpati, MD