List of CP cannabinoids

From WikiMD's Food, Medicine & Wellness Encyclopedia

CP cannabinoids are a group of synthetic cannabinoids that were first synthesized by Pfizer in the 1970s and 1980s. These compounds are part of a larger family of cannabinoids, which also includes natural compounds found in the cannabis plant, as well as other synthetic compounds. CP cannabinoids are named after the company that first synthesized them (CP stands for "Charles Pfizer").

History[edit | edit source]

The first CP cannabinoid, CP 47,497, was synthesized in 1975 by a team of chemists at Pfizer. This compound, along with its homologues and analogues, were initially developed as part of research into new analgesic drugs. However, they have since been found to have a wide range of other effects, including psychoactive effects.

Structure and activity[edit | edit source]

CP cannabinoids are characterized by a three-ring structure, with a central cyclohexene ring flanked by two phenyl rings. The specific structure of the CP cannabinoid determines its activity at the cannabinoid receptors CB1 and CB2.

List of CP cannabinoids[edit | edit source]

  • CP 47,497: The first CP cannabinoid to be synthesized. It is a potent agonist at the CB1 receptor.
  • CP 55,940: A derivative of CP 47,497, it is one of the most potent cannabinoids known, with a high affinity for both the CB1 and CB2 receptors.
  • CP 56,667: This compound is a selective CB2 receptor agonist, with little activity at the CB1 receptor.

Legal status[edit | edit source]

In many countries, including the United States, CP cannabinoids are classified as controlled substances. This is due to their psychoactive effects and potential for abuse.

See also[edit | edit source]

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Contributors: Prab R. Tumpati, MD