2,5-Dimethoxy-4-(2-fluoroethyl)amphetamine
2,5-Dimethoxy-4-(2-fluoroethyl)amphetamine[edit | edit source]
amphetamine.svg)
2,5-Dimethoxy-4-(2-fluoroethyl)amphetamine (also known as DOEF) is a psychedelic amphetamine of the substituted amphetamine class. It is a derivative of the phenethylamine 2C-E, with a fluorine atom replacing the ethyl group at the 4-position of the aromatic ring.
Chemical Structure[edit | edit source]
2,5-Dimethoxy-4-(2-fluoroethyl)amphetamine is a member of the substituted amphetamines, which are characterized by the presence of a phenethylamine core with an alpha-methyl group. The chemical structure of DOEF includes two methoxy groups at the 2 and 5 positions of the aromatic ring, and a 2-fluoroethyl group at the 4 position.
Pharmacology[edit | edit source]
DOEF acts as a serotonin receptor agonist, primarily affecting the 5-HT2A receptor. This action is responsible for its psychedelic effects. The compound is structurally similar to other psychedelic amphetamines such as DOM and DOI, which are known for their potent hallucinogenic properties.
Effects[edit | edit source]
The effects of 2,5-Dimethoxy-4-(2-fluoroethyl)amphetamine are similar to those of other psychedelic amphetamines. Users report altered states of consciousness, visual and auditory hallucinations, and changes in perception of time and space. The intensity and duration of these effects can vary depending on the dose and individual sensitivity.
Synthesis[edit | edit source]
The synthesis of DOEF involves the introduction of a 2-fluoroethyl group to the 4-position of the aromatic ring of 2,5-dimethoxyamphetamine. This is typically achieved through a series of chemical reactions starting from 2,5-dimethoxybenzaldehyde.
Legal Status[edit | edit source]
The legal status of 2,5-Dimethoxy-4-(2-fluoroethyl)amphetamine varies by country. In many jurisdictions, it is considered a controlled substance due to its structural similarity to other regulated psychedelic compounds.
Related Compounds[edit | edit source]
- 2,5-Dimethoxy-4-ethylamphetamine (DOET)
- 2,5-Dimethoxy-4-iodoamphetamine (DOI)
- 2,5-Dimethoxy-4-methylamphetamine (DOM)
- 2C-E
See Also[edit | edit source]
Related Pages[edit | edit source]
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates, categories Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
