CUMYL-PICA

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CUMYL-PICA is a compound that belongs to the class of drugs known as synthetic cannabinoids. It is a potent agonist of the CB1 receptor and CB2 receptor, which are part of the endocannabinoid system in the human body. CUMYL-PICA is often used in scientific research, but it has also been found in synthetic cannabis products sold for recreational use.

Chemistry[edit | edit source]

CUMYL-PICA is a derivative of indole and is structurally related to other synthetic cannabinoids such as 5F-PB-22 and BB-22. It has a cumyl group, which is a functional group consisting of a phenyl group attached to a tert-butyl group, attached to the indole ring through an amide linkage. The specific name CUMYL-PICA refers to the particular structure of this compound, where PICA stands for "PIndoleCArboxamide".

Pharmacology[edit | edit source]

As an agonist of the CB1 and CB2 receptors, CUMYL-PICA can produce effects similar to those of cannabis. However, due to its synthetic nature and the potential for variations in its chemical structure, the effects of CUMYL-PICA can be unpredictable and potentially harmful. The exact mechanisms of action of CUMYL-PICA are not fully understood, but it is thought to work by mimicking the effects of naturally occurring endocannabinoids in the body.

Legal Status[edit | edit source]

The legal status of CUMYL-PICA varies by country. In some countries, it is classified as a controlled substance due to its potential for abuse and the health risks associated with its use. In other countries, it is legal to possess and use CUMYL-PICA for research purposes.

See Also[edit | edit source]

References[edit | edit source]


CUMYL-PICA Resources
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Contributors: Prab R. Tumpati, MD