JWH-198
JWH-198 is a synthetic cannabinoid from the naphthoylindole family, which acts as a full agonist at both the CB1 and CB2 cannabinoid receptors, but with moderate selectivity for CB2. It was discovered by and named after Dr. John W. Huffman.
Chemistry[edit | edit source]
JWH-198 is part of the naphthoylindole family of synthetic cannabinoids. It is structurally related to other synthetic cannabinoids including JWH-018, JWH-073, and JWH-200. The compound is a full agonist at both the CB1 and CB2 cannabinoid receptors, but it has moderate selectivity for the CB2 receptor.
Pharmacology[edit | edit source]
As a full agonist at the CB1 and CB2 receptors, JWH-198 can produce a wide range of effects similar to those of cannabis. These effects can include relaxation, euphoria, and altered perception. However, because it is a synthetic compound, the effects of JWH-198 can be more potent and unpredictable than those of natural cannabis.
Legal Status[edit | edit source]
The legal status of JWH-198 varies by country and region. In some places, it is classified as a controlled substance due to its potential for abuse and its psychoactive effects. In others, it may be legal to possess and use. It is important to check local laws before possessing or using this substance.
See Also[edit | edit source]
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Contributors: Prab R. Tumpati, MD