DOx

DOx is a chemical class of substituted amphetamine compounds that have potent psychedelic effects, including 4-FA; some, like DOM, have been used recreationally. The DOx family includes DOB, DOC, DOI and others.

History

The term DOx refers to a broad class of chemicals which include DOB, DOC, DOI and others. These compounds were first synthesized by Alexander Shulgin in the 1960s and 1970s. In his book PiHKAL (Phenethylamines I Have Known And Loved), Shulgin lists the dosage range for DOB as 1-3 mg, the duration as 18–30 hours, and the effects as "very strong, long duration, psychedelic".

Pharmacology

DOx compounds are often taken orally, and many have a long onset of action, often two to three hours. The effects of DOx compounds can last from 14 to 20 hours. DOx compounds are partial agonists at the 5-HT2A receptor and have a high affinity for the 5-HT2B receptor and the 5-HT2C receptor.

Effects

The effects of DOx compounds are similar to those of other psychedelic drugs. The user may experience visual hallucinations, changes in mood, introspection, euphoria, and altered perception of time and space. At high doses or in sensitive individuals, these effects can be overwhelming and can cause panic attacks, confusion, and delirium.

Legal status

The legal status of DOx compounds varies from country to country. Many countries have laws that ban the manufacture, sale, and possession of DOx compounds. In the United States, DOx compounds are classified as Schedule I controlled substances.

See also

• Phenethylamine
• Psychedelic drug
• Recreational drug use

References

DOx Resources
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