2,3-Dihydroxybenzoic acid

From WikiMD's Food, Medicine & Wellness Encyclopedia

2,3-Dihydroxybenzoic acid (also known as 2,3-DHBA) is an organic compound that belongs to the class of benzoic acids. It is a dihydroxybenzoic acid where the two hydroxy groups are located at positions 2 and 3.

Chemical Properties[edit | edit source]

2,3-Dihydroxybenzoic acid is a white to light yellow crystalline powder. It is soluble in water, alcohol, and ether. It has a melting point of 200-202 °C and a boiling point of 446.9 °C at 760 mmHg.

Synthesis[edit | edit source]

2,3-Dihydroxybenzoic acid can be synthesized from salicylic acid through a process known as Fries rearrangement. This involves the acylation of salicylic acid with acetic anhydride, followed by rearrangement in the presence of a Lewis acid catalyst.

Applications[edit | edit source]

2,3-Dihydroxybenzoic acid is used as a precursor in the synthesis of various pharmaceuticals and agrochemicals. It is also used in the production of dyes and pigments, and as a chelating agent in analytical chemistry.

Safety[edit | edit source]

As with all chemicals, 2,3-Dihydroxybenzoic acid should be handled with care. It may cause irritation to the skin and eyes, and may be harmful if swallowed or inhaled.

See Also[edit | edit source]

References[edit | edit source]


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Contributors: Prab R. Tumpati, MD