2,3-Dimercapto-1-propanesulfonic acid

From WikiMD's Wellness Encyclopedia

2,3-Dimercapto-1-propanesulfonic acid


2,3-Dimercapto-1-propanesulfonic acid (also known as DMPS) is a water-soluble compound that is used as a chelating agent. It is particularly effective in the treatment of heavy metal poisoning, including mercury, arsenic, and lead poisoning.

History[edit | edit source]

DMPS was first synthesized in the 1950s by the Heyl Brothers company in Berlin, Germany. It was initially used in the treatment of arsenic poisoning, but its use has since expanded to include other types of heavy metal poisoning.

Pharmacology[edit | edit source]

DMPS works by binding to heavy metals in the body, forming a stable complex that can be excreted in the urine. This process is known as chelation therapy. DMPS is a dithiol compound, meaning it has two sulfhydryl groups which are responsible for its chelating properties.

Uses[edit | edit source]

DMPS is used in the treatment of acute and chronic heavy metal poisoning. It is particularly effective in cases of mercury, arsenic, and lead poisoning. It is also used in the diagnosis of these conditions, as the amount of metal excreted in the urine after administration of DMPS can give an indication of the level of metal exposure.

Side Effects[edit | edit source]

Like all medications, DMPS can have side effects. These can include nausea, vomiting, diarrhea, and rash. In rare cases, it can cause more serious side effects such as kidney damage and hypotension.

See Also[edit | edit source]

References[edit | edit source]


WikiMD
Navigation: Wellness - Encyclopedia - Health topics - Disease Index‏‎ - Drugs - World Directory - Gray's Anatomy - Keto diet - Recipes

Search WikiMD

Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD

WikiMD's Wellness Encyclopedia

Let Food Be Thy Medicine
Medicine Thy Food - Hippocrates

Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.

Contributors: Prab R. Tumpati, MD