From WikiMD's Food, Medicine & Wellness Encyclopedia

2,6-Di-tert-butylphenol is an organic compound that belongs to the class of phenols. This compound is characterized by the presence of two tert-butyl groups attached to the 2nd and 6th carbon atoms of the phenol ring.

Chemical Properties[edit | edit source]

2,6-Di-tert-butylphenol is a white, crystalline solid at room temperature. It has a melting point of 21.5-23.5 °C and a boiling point of 257-258 °C. It is slightly soluble in water but readily soluble in organic solvents such as ethanol, acetone, and diethyl ether.

Synthesis[edit | edit source]

The synthesis of 2,6-Di-tert-butylphenol is typically achieved through the Friedel-Crafts alkylation of phenol with isobutene in the presence of an acid catalyst such as sulfuric acid or hydrofluoric acid.

Applications[edit | edit source]

2,6-Di-tert-butylphenol is primarily used as an antioxidant in the production of industrial lubricants and biodiesel. It is also used in the manufacture of other antioxidants, such as butylated hydroxytoluene (BHT), which are used in food, cosmetics, and pharmaceuticals.

Safety and Environmental Concerns[edit | edit source]

While 2,6-Di-tert-butylphenol is not considered highly toxic, it can cause irritation to the skin and eyes. It is also harmful if swallowed or inhaled. This compound is not readily biodegradable and can accumulate in the environment, posing potential risks to aquatic life.

See Also[edit | edit source]


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Contributors: Prab R. Tumpati, MD