From WikiMD's Food, Medicine & Wellness Encyclopedia

2-Methylnaphthalene-1,4-diamine is a chemical compound with the formula C11H12N2. It is a derivative of naphthalene, a polycyclic aromatic hydrocarbon (PAH), with two amine groups attached at the 1 and 4 positions and a methyl group at the 2 position.

Structure and Properties[edit | edit source]

The structure of 2-methylnaphthalene-1,4-diamine consists of a naphthalene core, which is a fused two-ring system, with a methyl group attached at the 2 position and two amine groups attached at the 1 and 4 positions. The presence of the amine groups imparts basicity to the molecule, while the methyl group provides some degree of hydrophobicity.

The compound is a solid at room temperature and exhibits typical aromatic properties, such as stability and planarity. The presence of the amine groups allows it to participate in hydrogen bonding and other polar interactions.

Synthesis[edit | edit source]

The synthesis of 2-methylnaphthalene-1,4-diamine typically involves the nitration of 2-methylnaphthalene to form 2-methylnaphthalene-1,4-dinitro, followed by reduction of the nitro groups to form the diamine. The nitration step is usually carried out using a mixture of concentrated nitric acid and sulfuric acid, while the reduction step can be achieved using a variety of reducing agents, such as iron in hydrochloric acid or tin in hydrochloric acid.

Applications[edit | edit source]

2-Methylnaphthalene-1,4-diamine is primarily used in the synthesis of other chemical compounds. It can act as a building block in the synthesis of various polymers, dyes, and pharmaceuticals. Its ability to form multiple hydrogen bonds makes it useful in the creation of supramolecular structures.

Safety and Environmental Concerns[edit | edit source]

Like other aromatic amines, 2-methylnaphthalene-1,4-diamine can be hazardous to health. It can cause skin and eye irritation, and prolonged or repeated exposure can lead to more serious health effects. It is also potentially harmful to the environment, particularly aquatic ecosystems.


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Contributors: Prab R. Tumpati, MD