2-Thiouracil
2-Thiouracil is a chemical compound that is classified as a pyrimidinedione. It is a derivative of uracil, a component of RNA, where an oxygen atom is replaced by a sulfur atom.
Structure and properties[edit | edit source]
2-Thiouracil has a molecular formula of C4H4N2OS. It is a solid substance at room temperature and has a molar mass of 128.15 g/mol. The compound is a derivative of uracil, which is one of the four nucleobases in the nucleic acid of RNA. In 2-thiouracil, one of the oxygen atoms in uracil is replaced by a sulfur atom.
Synthesis[edit | edit source]
2-Thiouracil can be synthesized from urea and carbon disulfide in the presence of ammonia. The reaction proceeds through the formation of thiourea, which is then cyclized to form 2-thiouracil.
Applications[edit | edit source]
2-Thiouracil is used in the synthesis of various pharmaceuticals. It is also used as a building block in the synthesis of more complex organic compounds.
See also[edit | edit source]
2-Thiouracil Resources | ||
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