2-methylquinoline

From WikiMD's Food, Medicine & Wellness Encyclopedia

2-Methylquinoline is an organic compound with the formula C10H9N. It is a derivative of quinoline with a methyl group substituted onto the second carbon atom of the quinoline ring structure. This compound is a colorless liquid that is slightly soluble in water but more soluble in organic solvents. It is used in the synthesis of various pharmaceuticals and other organic compounds.

Structure and Properties[edit | edit source]

2-Methylquinoline is a heterocyclic compound consisting of a benzene ring fused to a pyridine ring. The methyl group is attached to the second carbon atom of the quinoline ring. This compound is a colorless liquid at room temperature and has a characteristic, somewhat unpleasant odor.

The molecular formula of 2-methylquinoline is C10H9N, and its molar mass is 143.19 g/mol. It has a boiling point of 273-275 °C and a melting point of -15 °C. The compound is slightly soluble in water but more soluble in organic solvents such as ethanol and diethyl ether.

Synthesis[edit | edit source]

2-Methylquinoline can be synthesized by the Skraup reaction, a method for the synthesis of quinolines. In this reaction, aniline is heated with sulfuric acid, glycerol, and an oxidizing agent. The resulting product is then alkylated with a methyl group to yield 2-methylquinoline.

Applications[edit | edit source]

2-Methylquinoline is used in the synthesis of various pharmaceuticals and other organic compounds. It is also used as a starting material in the production of dyes and pigments.

Safety and Toxicity[edit | edit source]

Like many organic compounds, 2-methylquinoline is flammable and should be handled with care. It can cause irritation to the skin and eyes, and prolonged exposure can lead to more serious health effects. Always use appropriate safety measures when handling this compound.

See Also[edit | edit source]

References[edit | edit source]


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Contributors: Prab R. Tumpati, MD