2C2-NBOMe

From WikiMD's Food, Medicine & Wellness Encyclopedia

2C2-NBOMe is a psychedelic phenethylamine of the 2C family. It was first synthesized by Alexander Shulgin and later reported in his book PiHKAL: A Chemical Love Story. The full name of the chemical is 2-(2,5-dimethoxy-4-bromophenyl)-N-[(2-methoxyphenyl)methyl]ethanamine.

Chemistry[edit | edit source]

2C2-NBOMe is a derivative of the 2C family of phenethylamines described by Alexander Shulgin in his book PiHKAL. The chemical structure consists of a phenethylamine core, with an additional methoxy group at the 2 and 5 positions of the phenyl ring, and a bromo group at the 4 position. The NBOMe addition consists of a methoxybenzyl group attached to the nitrogen of the phenethylamine backbone.

Pharmacology[edit | edit source]

2C2-NBOMe acts as a highly potent partial agonist for the 5-HT2A receptor. The precise mechanism of action is not fully understood, but it is thought to involve a complex interplay between various neurotransmitter systems, including the serotonergic, dopaminergic, and glutamatergic systems.

Effects[edit | edit source]

The effects of 2C2-NBOMe can vary greatly depending on the dose, set, and setting. At lower doses, effects can include feelings of euphoria, enhanced sensory perception, and increased empathy. At higher doses, effects can include intense hallucinations, delusions, and a loss of sense of self. The duration of effects can range from 4 to 12 hours.

Risks[edit | edit source]

2C2-NBOMe is a relatively new substance, and as such, the long-term effects are not well understood. However, there have been reports of severe adverse reactions, including seizures, psychosis, and death. It is strongly advised to use harm reduction practices when using this substance.

Legal Status[edit | edit source]

The legal status of 2C2-NBOMe varies by country. In many countries, it is a controlled substance, making it illegal to manufacture, distribute, or possess.

See Also[edit | edit source]

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Contributors: Prab R. Tumpati, MD