3,14-Diacetyloxymorphone

3,14-Diacetyloxymorphone is a semi-synthetic opioid derivative of morphine. It is often used in the medical field for its analgesic properties.

Chemistry[edit | edit source]

3,14-Diacetyloxymorphone is a derivative of morphine, which is a naturally occurring opioid found in the opium poppy. It is created by acetylating the 3 and 14 hydroxyl groups of morphine. The resulting compound has increased potency and duration of action compared to morphine.

Pharmacology[edit | edit source]

The pharmacology of 3,14-Diacetyloxymorphone is similar to that of other opioids. It acts primarily on the mu-opioid receptor, producing analgesia, sedation, and euphoria. It also has effects on the kappa-opioid receptor and delta-opioid receptor, although these are less pronounced.

Medical Use[edit | edit source]

3,14-Diacetyloxymorphone is used in the treatment of moderate to severe pain. It is often used in patients who have developed a tolerance to other opioids. Its long duration of action makes it suitable for use in chronic pain management.

Side Effects[edit | edit source]

Like all opioids, 3,14-Diacetyloxymorphone has a number of potential side effects. These include nausea, vomiting, constipation, and respiratory depression. Long-term use can lead to opioid dependence and withdrawal symptoms upon cessation of use.