3,4-Dichloromethylphenidate

3,4-Dichloromethylphenidate (3,4-DCMP) is a stimulant drug related to methylphenidate. Methylphenidate is a central nervous system (CNS) stimulant of the phenethylamine and piperidine classes. 3,4-DCMP is a derivative of methylphenidate, distinguished by the presence of a dichloro substitution on the phenyl ring.

Chemistry

3,4-Dichloromethylphenidate belongs to the family of Phenidates, which are compounds containing a phenylacetate moiety. It is a derivative of methylphenidate, with the molecular formula C14H17Cl2NO2. The systematic name of this compound is methyl 2-(3,4-dichlorophenyl)-2-(piperidin-2-yl)acetate.

Pharmacology

The exact mechanism of action of 3,4-DCMP is not fully understood. However, it is believed to work by blocking the reuptake of dopamine and norepinephrine into the presynaptic neuron, increasing the levels of these neurotransmitters in the synaptic cleft. This results in increased neurotransmission and leads to increased alertness, attention, and energy.

Medical Uses

3,4-Dichloromethylphenidate has been used as a potential treatment for ADHD and narcolepsy. However, its use is not widespread due to the lack of extensive clinical trials and potential for abuse.

Side Effects

Potential side effects of 3,4-DCMP include insomnia, anxiety, increased heart rate, and increased blood pressure. Long-term use can lead to dependence and withdrawal symptoms upon cessation.

See Also

• Methylphenidate
• Dopamine
• Norepinephrine
• ADHD
• Narcolepsy