3,4-Ethylenedioxyamphetamine

Chemical compound

3,4-Ethylenedioxyamphetamine
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CAS Number	5401-87-8
PubChem	10024
DrugBank
ChemSpider	9630
KEGG

3,4-Ethylenedioxyamphetamine (EDA) is a psychoactive drug and a member of the amphetamine class of compounds. It is structurally related to 3,4-methylenedioxyamphetamine (MDA) and is known for its stimulant and empathogen effects. EDA is not widely used recreationally and has limited research regarding its pharmacological properties.

Chemical Structure and Properties

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Chemical structure of 3,4-Ethylenedioxyamphetamine

3,4-Ethylenedioxyamphetamine is characterized by the presence of a 1,3-benzodioxole ring attached to an amphetamine backbone. The chemical formula is C₁₀H₁₃NO₂, and it has a molecular weight of 179.22 g/mol. The compound is a derivative of amphetamine, with the methylenedioxy group contributing to its psychoactive properties.

Pharmacology

EDA acts primarily as a central nervous system stimulant. It is believed to increase the release of neurotransmitters such as dopamine, serotonin, and norepinephrine, similar to other amphetamines. This action results in increased alertness, energy, and mood elevation. However, the specific binding affinities and receptor interactions of EDA are not well-documented in scientific literature.

Effects

The effects of 3,4-ethylenedioxyamphetamine are similar to those of other empathogens and stimulants. Users may experience increased sociability, empathy, and euphoria. Physical effects can include increased heart rate, blood pressure, and body temperature. Due to its limited use and research, the full spectrum of effects and potential risks are not fully understood.

Legal Status

The legal status of 3,4-ethylenedioxyamphetamine varies by country. In many jurisdictions, it is classified as a controlled substance due to its structural similarity to other regulated amphetamines. It is not approved for medical use and is primarily encountered in research settings.

Synthesis

The synthesis of 3,4-ethylenedioxyamphetamine involves the reaction of 3,4-methylenedioxyphenylacetone with ammonia and a reducing agent. This process is similar to the synthesis of other amphetamine derivatives. Due to its potential for misuse, the synthesis of EDA is subject to legal restrictions in many areas.

Related Compounds

• 3,4-Methylenedioxyamphetamine (MDA)
• 3,4-Methylenedioxymethamphetamine (MDMA)
• Amphetamine

Related Pages

• Psychoactive drug
• Empathogen
• Stimulant