3-Chloromethamphetamine

3-Chloromethamphetamine

3-Chloromethamphetamine is a psychoactive drug and research chemical of the phenethylamine and amphetamine chemical classes. It acts as a selective serotonin releasing agent (SSRA) with negligible effects on dopamine and norepinephrine.

Chemistry

3-Chloromethamphetamine is a substituted amphetamine with a chemical structure closely related to methamphetamine, differing only in the addition of a chlorine atom on the phenyl ring. This substitution significantly alters the pharmacological properties of the compound.

Pharmacology

As a selective serotonin releasing agent, 3-Chloromethamphetamine primarily promotes the release of serotonin from serotonergic neurons in the brain. This leads to increased extracellular concentrations of serotonin and therefore an increase in serotonergic neurotransmission.

Effects

The effects of 3-Chloromethamphetamine are largely similar to those of other serotonin releasing agents, including feelings of euphoria, increased sociability, and heightened mood. However, due to its selectivity for serotonin, it does not produce the stimulant, euphoric, or nootropic effects typically associated with compounds that also release dopamine and norepinephrine.

Toxicity and Harm Potential

The toxicity and long-term health effects of recreational 3-Chloromethamphetamine use do not seem to have been studied in any scientific context and the exact toxic dosage is unknown. However, as with all serotonin releasing agents, there is a strong potential for neurotoxicity and long-term damage to the brain's serotonin system with heavy use or prolonged exposure.

Legal Status

The legal status of 3-Chloromethamphetamine varies by country, but it is often considered a controlled substance due to its potential for abuse and addiction.

See Also

• Methamphetamine
• Amphetamine
• Serotonin releasing agent
• Substituted amphetamine