3-MeO-PCMo

3-MeO-PCMo

3-MeO-PCMo is a chemical compound belonging to the aryl cyclohexylamine class. It is a dissociative anesthetic that is structurally related to phencyclidine (PCP) and methoxetamine (MXE).

Chemistry

3-MeO-PCMo, or 3-Methoxyphencyclidin-4-ylmorpholine, is an aryl cyclohexylamine compound. The structure of 3-MeO-PCMo consists of a phenyl ring bound to a cyclohexylamine unit with an additional morpholine ring. The "3-MeO" in its name refers to a methoxy group positioned at the 3rd position of the phenyl ring.

Pharmacology

As a member of the aryl cyclohexylamine class, 3-MeO-PCMo acts primarily as an NMDA receptor antagonist. NMDA receptors allow for electrical signals to pass between neurons in the brain and spinal column; for the signals to pass, the receptor must be open. Dissociatives like 3-MeO-PCMo close the NMDA receptors by blocking them. This disconnection of neurons leads to loss of normal sensory perception, hence the term "dissociative."

Effects

The effects of 3-MeO-PCMo are often compared to those of other dissociative anesthetics such as ketamine, DXM, and nitrous oxide. Users report feelings of derealization, depersonalization, and hallucination. The intensity and duration of these effects are dose-dependent and can vary significantly among individuals.

Legality

The legality of 3-MeO-PCMo varies by country. In some countries, it is a controlled substance, while in others, it remains legal. It is always important to understand the legal status of a substance in one's own jurisdiction before possession or use.

Safety

As with all substances, the use of 3-MeO-PCMo carries risks. It is a potent substance with a narrow safety margin, meaning the difference between an effective dose and a potentially harmful dose can be small. It is recommended to use harm reduction practices when using this substance.

See Also

• Phencyclidine
• Methoxetamine
• Dissociative
• Aryl cyclohexylamine