3-Methoxy-4-ethoxyphenethylamine
3-Methoxy-4-ethoxyphenethylamine is a chemical compound belonging to the class of organic compounds known as phenethylamines. Phenethylamines are compounds containing a phenethylamine moiety, which consists of a phenyl group substituted at the second position by an ethylamine.
Chemical Structure[edit | edit source]
The chemical structure of 3-Methoxy-4-ethoxyphenethylamine consists of a phenyl ring bonded to an ethylamine side chain at the para position. The phenyl ring is substituted at the third position by a methoxy group and at the fourth position by an ethoxy group.
Synthesis[edit | edit source]
The synthesis of 3-Methoxy-4-ethoxyphenethylamine can be achieved through the Friedel-Crafts alkylation of guaiacol with diethyl sulfate, followed by reductive amination with nitroethane.
Properties[edit | edit source]
3-Methoxy-4-ethoxyphenethylamine is a solid at room temperature. It is soluble in organic solvents such as ethanol, methanol, and dichloromethane.
Applications[edit | edit source]
While the specific applications of 3-Methoxy-4-ethoxyphenethylamine are not well-documented, phenethylamines in general have a wide range of uses in the fields of medicine, pharmacology, and neuroscience. They are often used in the synthesis of psychoactive drugs, antidepressants, and decongestants.
Safety[edit | edit source]
As with all chemical compounds, proper safety measures should be taken when handling 3-Methoxy-4-ethoxyphenethylamine. It is recommended to use personal protective equipment and work in a well-ventilated area.
See Also[edit | edit source]
- Phenethylamine
- Methoxy
- Ethoxy
- Friedel-Crafts alkylation
- Guaiacol
- Diethyl sulfate
- Nitroethane
- Reductive amination
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Contributors: Prab R. Tumpati, MD