3-Methoxy-4-ethoxyphenethylamine

3-Methoxy-4-ethoxyphenethylamine is a chemical compound belonging to the class of organic compounds known as phenethylamines. Phenethylamines are compounds containing a phenethylamine moiety, which consists of a phenyl group substituted at the second position by an ethylamine.

Chemical Structure

The chemical structure of 3-Methoxy-4-ethoxyphenethylamine consists of a phenyl ring bonded to an ethylamine side chain at the para position. The phenyl ring is substituted at the third position by a methoxy group and at the fourth position by an ethoxy group.

Synthesis

The synthesis of 3-Methoxy-4-ethoxyphenethylamine can be achieved through the Friedel-Crafts alkylation of guaiacol with diethyl sulfate, followed by reductive amination with nitroethane.

Properties

3-Methoxy-4-ethoxyphenethylamine is a solid at room temperature. It is soluble in organic solvents such as ethanol, methanol, and dichloromethane.

Applications

While the specific applications of 3-Methoxy-4-ethoxyphenethylamine are not well-documented, phenethylamines in general have a wide range of uses in the fields of medicine, pharmacology, and neuroscience. They are often used in the synthesis of psychoactive drugs, antidepressants, and decongestants.

Safety

As with all chemical compounds, proper safety measures should be taken when handling 3-Methoxy-4-ethoxyphenethylamine. It is recommended to use personal protective equipment and work in a well-ventilated area.

See Also

• Phenethylamine
• Methoxy
• Ethoxy
• Friedel-Crafts alkylation
• Guaiacol
• Diethyl sulfate
• Nitroethane
• Reductive amination

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