4'F-CUMYL-5F-PICA

From WikiMD's Food, Medicine & Wellness Encyclopedia

4'F-CUMYL-5F-PICA is a synthetic cannabinoid that is also known as SGT-263. It is a potent agonist of the CB1 receptor and CB2 receptor. The compound is part of the CUMYL-PEGACLONE series and was first identified in 2015. It is illegal in many countries due to its psychoactive properties.

Chemistry[edit | edit source]

4'F-CUMYL-5F-PICA is a derivative of CUMYL-PEGACLONE, which is itself a derivative of AB-CHMINACA. The compound has a 4-fluoro substitution on the phenyl ring, which is thought to increase its potency. The core structure of 4'F-CUMYL-5F-PICA is based on the indazole-3-carboxamide family of synthetic cannabinoids.

Pharmacology[edit | edit source]

As a synthetic cannabinoid, 4'F-CUMYL-5F-PICA acts as a potent agonist for the CB1 and CB2 receptors. The exact mechanism of action is not fully understood, but it is thought to mimic the effects of naturally occurring cannabinoids such as THC.

Legal Status[edit | edit source]

4'F-CUMYL-5F-PICA is illegal in many countries due to its psychoactive properties. In the United States, it is classified as a Schedule I controlled substance. In the United Kingdom, it is a Class B drug under the Misuse of Drugs Act.

See Also[edit | edit source]

4'F-CUMYL-5F-PICA Resources
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Contributors: Prab R. Tumpati, MD