4-Androstenediol

A steroid hormone and prohormone of testosterone

4-Androstenediol is a steroid hormone and a prohormone of testosterone. It is one of the androgens, which are hormones that play a role in male traits and reproductive activity. 4-Androstenediol is a naturally occurring compound in the human body and is involved in the biosynthesis of testosterone.

Chemical structure

4-Androstenediol is a steroid with the chemical formula C₁₉H₃₀O₂. It is structurally similar to testosterone and other androgens, with a characteristic four-ring carbon structure. The compound is also known by its systematic name, androst-4-ene-3_,17_-diol.

Biosynthesis

In the human body, 4-Androstenediol is synthesized from dehydroepiandrosterone (DHEA) and androstenedione through enzymatic reactions. These reactions are part of the steroidogenesis pathway, which is responsible for the production of steroid hormones from cholesterol.

Function

4-Androstenediol serves as a precursor to testosterone, which is a key hormone in the development of male secondary sexual characteristics, such as increased muscle and bone mass, and the growth of body hair. It also plays a role in the regulation of libido and spermatogenesis.

Medical use

While 4-Androstenediol itself is not commonly used in medical treatments, its role as a prohormone makes it of interest in the study of hormone replacement therapy and anabolic steroid use. It has been investigated for its potential to increase testosterone levels in individuals with low testosterone.

Regulation

Due to its potential to increase testosterone levels, 4-Androstenediol is classified as a controlled substance in many countries. It is included in the list of substances banned by the World Anti-Doping Agency (WADA) for use in sports.

Related pages

• Testosterone
• Androgen
• Steroid hormone
• Prohormone

Gallery

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  Structural formula of 4-Androstenediol

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  3D model of 4-Androstenediol

4-Androstenediol

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  Diagram of 4-Androstenediol

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  3D model of 4-Androstenediol