Anabolic steroid

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Anabolic steroids, also known as anabolic-androgenic steroids (AAS),[1] are steroidal androgens that include both natural androgens like testosterone and synthetic androgens that are structurally related and have similar effects to testosterone.

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Mechanism of Action[edit | edit source]

Anabolic steroids are anabolic, meaning they promote the growth of cells, particularly in skeletal muscle tissue. They also play a role in the development and maintenance of male secondary sexual characteristics, such as the growth of facial and body hair. The term "anabolic" comes from the Greek word anabole, meaning "that which is thrown up, mound".

History and Medical Uses[edit | edit source]

Androgens, or AAS, were first synthesized in the 1930s and have since been used in medicine for various purposes. They are prescribed to stimulate muscle growth, increase appetite, and induce male puberty. AAS can also be used to treat chronic wasting conditions, such as AIDS and cancer.[2]

Adverse Effects and Health Risks[edit | edit source]

Long-term use of anabolic steroids can lead to harmful health effects, including detrimental changes in cholesterol levels, acne, high blood pressure, and liver damage. The severity and duration of these side effects depend on factors such as dosage, duration of use, and individual susceptibility.

Controversy and Doping[edit | edit source]

The use of anabolic steroids in sports, racing, and bodybuilding as performance-enhancing drugs is controversial due to their adverse effects and the potential for gaining an unfair advantage in physical competitions. Their use in sports is known as doping, and most major sporting bodies have banned the use of anabolic steroids.

See Also[edit | edit source]

References[edit | edit source]

  1. "Pharmacology of Anabolic Steroids". The British Journal of Pharmacology. Retrieved October 19, 2018.
Anabolic steroid Resources
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Contributors: Prab R. Tumpati, MD