4-Methylcathinone

4-Methylcathinone

4-Methylcathinone (4-MC), also known as mephedrone, is a synthetic stimulant drug of the amphetamine and cathinone classes. Slang names include meph, drone, and meow meow. It is chemically similar to the cathinone compounds found in the khat plant of eastern Africa. It comes in the form of tablets or a powder, which users can swallow, snort, inject, or use rectally.

Chemistry

4-Methylcathinone is a synthetic molecule of the cathinone family. Cathinones are structurally similar to amphetamines, differing by the addition of a β-keto group. The chemical formula for 4-Methylcathinone is C11H15NO. It features a phenethylamine core with an alkyl group attached to the alpha carbon and an oxygen group attached to the beta carbon. Mephedrone specifically has a methyl group at the 4 position of the phenyl ring.

Pharmacology

The mechanism of action of 4-Methylcathinone is similar to other stimulants, primarily acting as a releasing agent of dopamine, serotonin, and norepinephrine. This results in increased concentrations of these neurotransmitters in the brain, leading to stimulant effects along with euphoria, increased alertness, and a sense of well-being. Its effects are often compared to those of cocaine, MDMA, and other synthetic stimulants.

Effects

The effects of 4-Methylcathinone can vary depending on the dose, method of administration, and individual sensitivity. Common effects include euphoria, increased energy, talkativeness, and heightened senses. Adverse effects may include palpitations, sweating, nausea, and increased blood pressure. High doses and frequent use can lead to more severe health issues, including addiction, cardiac problems, and mental health disorders such as anxiety and paranoia.

Legality

The legal status of 4-Methylcathinone varies by country. It has been made illegal in many countries due to concerns over its potential for abuse, addiction, and health risks. In some jurisdictions, it is controlled under analogue laws, making it illegal to sell, buy, or possess without a license.

History

4-Methylcathinone first appeared on the recreational drug market in the early 2000s. It gained popularity as a legal alternative to other illicit stimulants. Its use peaked in the late 2000s, leading to increased media attention and concerns from health professionals. This resulted in legislative action in several countries to control its distribution and use.

See Also

• Cathinone
• Amphetamine
• Psychoactive drug
• Drug abuse