4-Propionyloxy-DMT

4-Propionyloxy-DMT (also known as 4-PO-DMT or Psilopropanoyl) is a psychedelic drug and a serotonin receptor agonist. It is a prodrug of psilocin, a compound found in many species of psychedelic mushrooms.

Chemistry

4-Propionyloxy-DMT is a synthetic compound and belongs to the class of tryptamines. It is structurally similar to psilocin, differing only by the addition of a propionyloxy group. This modification allows the compound to be metabolized into psilocin in the body.

Pharmacology

As a prodrug of psilocin, 4-Propionyloxy-DMT is inactive until it is metabolized in the body. The propionyloxy group is cleaved off during metabolism, yielding psilocin, which then acts as an agonist at the 5-HT2A receptor. This receptor is known to play a key role in the cognitive effects of psychedelics.

Effects

The effects of 4-Propionyloxy-DMT are similar to those of other psychedelic drugs. Users may experience alterations in perception, mood, thought, and consciousness. These effects can include visual and auditory hallucinations, euphoria, and introspective experiences.

Legal Status

The legal status of 4-Propionyloxy-DMT varies by country. In some jurisdictions, it is classified as a Schedule I drug, meaning it is illegal to manufacture, distribute, or possess.

Safety

As with all psychedelic substances, the use of 4-Propionyloxy-DMT carries risks. These can include psychological distress, dangerous behavior, and negative interactions with other substances. It is recommended that users take precautions such as having a sober sitter present and starting with a low dose.

See Also

• Psilocybin
• Psilocin
• Tryptamine
• Psychedelic drug
• Serotonin receptor