4-androstene-3,6,17-trione
4-Androstene-3,6,17-trione (also known as 4-AT or 6-OXO) is a steroid that has been marketed as a dietary supplement. It is a metabolite of androstenedione and dehydroepiandrosterone (DHEA), two hormones that can be converted into testosterone.
Chemical Structure and Properties[edit | edit source]
4-Androstene-3,6,17-trione is a steroid with the molecular formula C19H24O3. It has a molecular weight of 300.39 g/mol. The compound has three ketone groups, located at the 3, 6, and 17 positions of the steroid structure.
Uses and Effects[edit | edit source]
4-Androstene-3,6,17-trione is often used as a testosterone booster in dietary supplements. It is believed to work by inhibiting the enzyme aromatase, which converts testosterone into estrogen. By blocking this conversion, 4-AT can theoretically increase levels of testosterone in the body. However, scientific evidence supporting these effects is limited.
Safety and Legal Status[edit | edit source]
The safety of 4-Androstene-3,6,17-trione is not well-studied. Some reports suggest that it may have side effects similar to other anabolic steroids, including liver damage and increased risk of heart disease. In many countries, including the United States, 4-AT is classified as a controlled substance and is not legal for sale as a dietary supplement.
See Also[edit | edit source]
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Contributors: Prab R. Tumpati, MD