5-Benzyloxytryptamine

From WikiMD's Food, Medicine & Wellness Encyclopedia

5-Benzyloxytryptamine (also known as 5-BOT) is a tryptamine derivative that is used in scientific research. It is a serotonin receptor agonist, meaning it can stimulate the serotonin receptors in the brain.

Chemistry[edit | edit source]

5-Benzyloxytryptamine is a derivative of the naturally occurring amino acid tryptamine. It has a benzyl group attached to the oxygen atom at the 5-position of the tryptamine molecule. This modification increases the lipophilicity of the molecule, which can enhance its ability to cross the blood-brain barrier.

Pharmacology[edit | edit source]

As a serotonin receptor agonist, 5-Benzyloxytryptamine can stimulate the serotonin receptors in the brain. Serotonin is a neurotransmitter that plays a key role in mood, appetite, sleep, and other functions. By stimulating the serotonin receptors, 5-Benzyloxytryptamine can potentially influence these functions.

Research Uses[edit | edit source]

5-Benzyloxytryptamine is used in scientific research to study the serotonin system in the brain. It can be used to investigate the role of serotonin in various physiological and psychological processes, as well as the potential therapeutic effects of serotonin receptor agonists.

Safety[edit | edit source]

As a research chemical, 5-Benzyloxytryptamine is not intended for human consumption. Its safety profile in humans is not well-studied, and it should be handled with caution in a laboratory setting.

See Also[edit | edit source]

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Contributors: Prab R. Tumpati, MD