5-Methoxytryptamine
5-Methoxytryptamine (5-MT), also known as Mexamine, is a tryptamine derivative closely related to the neurotransmitters serotonin and melatonin. 5-MT has been used as a tool in neuroscience to understand the serotonin system.
Chemistry[edit | edit source]
5-Methoxytryptamine is a member of the tryptamine class of compounds, specifically a monoamine derivative. It is structurally similar to other tryptamines such as DMT and psilocin, with the key difference being the addition of a methoxy group at the 5 position of the indole ring.
Pharmacology[edit | edit source]
5-MT acts as a non-selective serotonin receptor agonist, binding to a variety of serotonin receptors. It has been shown to have affinity for the 5-HT1, 5-HT2, 5-HT4, 5-HT6, and 5-HT7 receptors. The exact pharmacological profile of 5-MT is still under investigation.
Effects[edit | edit source]
The effects of 5-MT are not well-studied in humans. However, due to its structural and pharmacological similarities to other tryptamines, it is likely that it has similar effects. These may include alterations in perception, mood, and cognition, although this is purely speculative.
Legal Status[edit | edit source]
The legal status of 5-MT varies by country. In some countries, it is a controlled substance, while in others it is legal to possess and use.
See Also[edit | edit source]
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Contributors: Prab R. Tumpati, MD
