5-Methoxysalicylic acid

5-Methoxysalicylic acid

5-Methoxysalicylic acid is an organic compound that belongs to the class of phenols. It is a derivative of salicylic acid, with a methoxy group attached to the fifth carbon atom of the benzene ring.

Chemical Structure

The chemical structure of 5-Methoxysalicylic acid consists of a six-membered benzene ring, which is substituted by a carboxylic acid group at the second carbon atom and a methoxy group at the fifth carbon atom. The presence of these functional groups gives the compound its unique chemical properties.

Synthesis

5-Methoxysalicylic acid can be synthesized through the Friedel-Crafts alkylation of salicylic acid with dimethyl sulfate. This reaction involves the substitution of a hydrogen atom on the benzene ring with a methoxy group.

Properties

5-Methoxysalicylic acid is a white crystalline solid at room temperature. It is soluble in water, ethanol, and diethyl ether. The compound exhibits acidic properties due to the presence of the carboxylic acid group.

Applications

5-Methoxysalicylic acid is used in the synthesis of various pharmaceuticals and dyes. It is also used as a laboratory reagent in various chemical reactions.

Safety

As with all chemicals, 5-Methoxysalicylic acid should be handled with care. It can cause irritation to the skin and eyes, and may be harmful if swallowed or inhaled.

See Also

• Salicylic acid
• Methoxy
• Phenols
• Friedel-Crafts alkylation