6,6-Difluoronorethisterone
6,6-Difluoronorethisterone is a synthetic steroid that is related to nandrolone. It is a potent progestogen, but has weak androgenic and anabolic effects. It has been studied as a potential contraceptive.
Chemistry[edit | edit source]
6,6-Difluoronorethisterone is a synthetic androstane steroid and a derivative of testosterone. It is more specifically a derivative of nandrolone (19-nortestosterone) and is a member of the estrane (C18 steroid) family. It is also related to other 19-nortestosterone derivatives including noretynodrel and ethisterone.
Pharmacology[edit | edit source]
As a progestogen, 6,6-Difluoronorethisterone has the ability to bind to and activate the progesterone receptor. This leads to changes in the endometrium that make it unsuitable for implantation of a fertilized egg, thus preventing pregnancy. It also thickens the cervical mucus, making it difficult for sperm to reach the egg.
Despite its relation to nandrolone, 6,6-Difluoronorethisterone has only weak androgenic and anabolic effects. This is because it is not metabolized to a more potent androgenic or anabolic metabolite in the same way that nandrolone is.
History[edit | edit source]
6,6-Difluoronorethisterone was first synthesized in the 1960s as part of a search for more potent progestogens for use in contraceptives. It was found to be a potent progestogen, but its weak androgenic and anabolic effects made it less suitable for use as a contraceptive than other compounds that were being developed at the same time.
See also[edit | edit source]
This chemical compound related article is a stub. You can help WikiMD by expanding it.
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
WikiMD's Wellness Encyclopedia |
Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD