6-APB

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6-APB[edit | edit source]

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Chemical structure of 6-APB
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Ball-and-stick model of 6-APB
6-APB in powder form

6-APB (6-(2-aminopropyl)benzofuran) is a synthetic compound that is structurally related to MDMA and is part of the benzofuran class of drugs. It is known for its psychoactive effects and has been used recreationally as a designer drug.

Chemical Properties[edit | edit source]

6-APB is a member of the benzofuran family, which are compounds that contain a benzene ring fused to a furan ring. The chemical formula for 6-APB is C11H13NO, and it has a molecular weight of 175.23 g/mol. The compound is typically found in the form of a hydrochloride salt.

Pharmacology[edit | edit source]

6-APB acts primarily as a serotonin-norepinephrine-dopamine releasing agent (SNDRA). It increases the levels of these neurotransmitters in the brain, leading to its psychoactive effects. The compound is known to produce effects similar to those of MDMA, including euphoria, increased sociability, and enhanced sensory perception.

Effects[edit | edit source]

The effects of 6-APB can vary depending on the dose and individual sensitivity. Common effects include:

  • Euphoria
  • Increased energy and alertness
  • Enhanced empathy and sociability
  • Altered sensory perception
  • Mild hallucinations at higher doses

Synthesis[edit | edit source]

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Synthesis of 6-APB and its structural isomer 4-APB

The synthesis of 6-APB involves the reaction of 2-aminoindan with benzofuran-6-carboxaldehyde. This process results in the formation of the benzofuran ring system, which is a key structural component of the compound.

Legal Status[edit | edit source]

The legal status of 6-APB varies by country. In some jurisdictions, it is classified as a controlled substance, while in others it may be legal or unregulated. Users should be aware of the legal implications of possessing or using 6-APB in their region.

Related Compounds[edit | edit source]

6-APB is structurally related to several other compounds, including:

Related Pages[edit | edit source]

Gallery[edit | edit source]

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Contributors: Prab R. Tumpati, MD