60S ribosomal protein L6

Ideogram human chromosome 12

60S ribosomal protein L6

60S ribosomal protein L6 is a protein that in humans is encoded by the RPL6 gene. It is a component of the large subunit of the ribosome and plays a crucial role in protein synthesis. This protein is essential for the proper functioning of the ribosome and is highly conserved across different species.

Structure

60S ribosomal protein L6 is a structural component of the 60S ribosomal subunit. It is composed of a single polypeptide chain that folds into a specific three-dimensional structure. This structure allows the protein to interact with other ribosomal proteins and RNA molecules within the ribosome.

Function

As a ribosomal protein, 60S ribosomal protein L6 plays a key role in the translation of messenger RNA (mRNA) into proteins. It helps to stabilize the overall structure of the ribosome and is involved in the decoding of mRNA during protein synthesis. Additionally, this protein may also have other functions outside of its role in the ribosome.

Clinical Significance

Mutations in the RPL6 gene, which encodes 60S ribosomal protein L6, have been associated with certain genetic disorders. These mutations can disrupt normal protein synthesis and lead to various health conditions. Understanding the function of this protein is important for elucidating the molecular mechanisms underlying these disorders.