A-68930

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A-68930 is a drug that acts as a dopamine agonist. It is selective for the D1 and D5 subtypes.

Pharmacology[edit | edit source]

A-68930 is a dopamine agonist, which means it activates dopamine receptors in the absence of that ligand. The compound is selective for the D1 and D5 receptor subtypes, meaning it will not activate other dopamine receptors. This selectivity is important for the therapeutic effects of the drug, as different dopamine receptors are associated with different physiological responses.

Chemistry[edit | edit source]

A-68930 is a synthetic compound. Its chemical name is (R)-(+)-1-Phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol. The compound has a molecular weight of 247.3 g/mol.

Therapeutic Use[edit | edit source]

While A-68930 itself is not used therapeutically, it is an important research tool in the study of the dopamine system. By selectively activating D1 and D5 receptors, researchers can study the specific effects of these receptors in isolation from other dopamine receptors.

Side Effects[edit | edit source]

As a research tool, A-68930 is not typically administered to humans, so its side effect profile is not well known. However, as a dopamine agonist, it could theoretically cause side effects similar to those of other dopamine agonists, such as nausea, vomiting, and hallucinations.

See Also[edit | edit source]

A-68930 Resources
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Contributors: Prab R. Tumpati, MD