AB-PICA
AB-PICA is a chemical compound that is used in scientific research. It is a cannabinoid receptor agonist, with a binding affinity of 0.45nM at CB1 and 0.72nM at CB2. AB-PICA has been found to possess psychoactive properties in humans.
Chemistry[edit | edit source]
AB-PICA is a member of the aminoalkylindole class of synthetic cannabinoids. It is structurally related to compounds such as JWH-018 and ST-135, which share the aminoalkylindole base structure. The specific molecular structure of AB-PICA includes a naphthoyl group, which is substituted at the 1-position of the indole core, and an aminoalkyl group at the 3-position.
Pharmacology[edit | edit source]
AB-PICA acts as a full agonist at the CB1 receptor and the CB2 receptor, the two main types of cannabinoid receptors in the body. The CB1 receptor is primarily located in the brain and is responsible for the psychoactive effects of cannabinoids, while the CB2 receptor is found mainly in the immune system and is involved in immune response and inflammation.
Effects[edit | edit source]
The effects of AB-PICA in humans are not well-studied, but it is known to produce psychoactive effects. These may include euphoria, altered perception, and increased appetite. However, as with other synthetic cannabinoids, there may also be negative side effects such as anxiety, paranoia, and potentially serious health risks.
Legal Status[edit | edit source]
The legal status of AB-PICA varies by country. In some places, it is a controlled substance, while in others it may be legal to possess and use.
See Also[edit | edit source]
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