AB-PICA

AB-PICA is a chemical compound that is used in scientific research. It is a cannabinoid receptor agonist, with a binding affinity of 0.45nM at CB₁ and 0.72nM at CB₂. AB-PICA has been found to possess psychoactive properties in humans.

Chemistry

AB-PICA is a member of the aminoalkylindole class of synthetic cannabinoids. It is structurally related to compounds such as JWH-018 and ST-135, which share the aminoalkylindole base structure. The specific molecular structure of AB-PICA includes a naphthoyl group, which is substituted at the 1-position of the indole core, and an aminoalkyl group at the 3-position.

Pharmacology

AB-PICA acts as a full agonist at the CB1 receptor and the CB2 receptor, the two main types of cannabinoid receptors in the body. The CB1 receptor is primarily located in the brain and is responsible for the psychoactive effects of cannabinoids, while the CB2 receptor is found mainly in the immune system and is involved in immune response and inflammation.

Effects

The effects of AB-PICA in humans are not well-studied, but it is known to produce psychoactive effects. These may include euphoria, altered perception, and increased appetite. However, as with other synthetic cannabinoids, there may also be negative side effects such as anxiety, paranoia, and potentially serious health risks.

Legal Status

The legal status of AB-PICA varies by country. In some places, it is a controlled substance, while in others it may be legal to possess and use.

See Also

• Synthetic cannabinoids
• Cannabinoid receptor
• JWH-018
• ST-135

AB-PICA Resources
Need Help Finding a Doctor? WikiMD's DocFinder can help find general and specialist physicians.	Latest articles Most recent articles Ongoing trials.