ABCA10

ABCA10 is a gene that in humans encodes the ATP-binding cassette sub-family A member 10 protein. This protein is a member of the ATP-binding cassette transporter superfamily, which is one of the largest and most ancient protein families with members functioning from bacteria to humans.

Function

The ABCA10 protein is a member of the ABC transporters, which are a group of transmembrane proteins that utilize the energy from ATP hydrolysis to carry out certain biological processes including translocation of various substrates across membranes and non-transport related processes such as translation of RNA and DNA repair.

Clinical significance

ABCA10 has been implicated in several diseases. For instance, it has been associated with cancer, particularly lung cancer. Studies have shown that ABCA10 is overexpressed in lung cancer tissues, suggesting that it may play a role in the development and progression of the disease.

See also

• ATP-binding cassette transporter
• Transmembrane protein
• Lung cancer

References

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