ABCF1

ABCF1 (ATP-binding cassette sub-family F member 1) is a protein that in humans is encoded by the ABCF1 gene. This protein is a member of the ATP-binding cassette (ABC) transporter superfamily. ABC proteins transport various molecules across extra- and intra-cellular membranes.

Function

ABCF1 is a member of the ABC1 subfamily. Unlike other members of the ABC superfamily, ABCF1 lacks transmembrane domains and is thought to function in mRNA export from the nucleus to the cytoplasm. It has been suggested that ABCF1 may also be involved in the regulation of gene expression and cell growth.

Clinical significance

Mutations in the ABCF1 gene have been associated with a variety of diseases, including cancer, autoimmune diseases, and neurodegenerative diseases. In particular, overexpression of ABCF1 has been observed in several types of cancer, suggesting a potential role in tumor progression.

Research

Research into the function and potential therapeutic applications of ABCF1 is ongoing. Studies have suggested that ABCF1 may be a potential target for cancer therapy, and further research is needed to fully understand its role in disease progression and treatment.

See also

• ATP-binding cassette transporter
• Gene expression
• Cell growth

References

‎

---

Translate: - East Asian 中文, 日本, 한국어, South Asian हिन्दी, தமிழ், తెలుగు, Urdu, ಕನ್ನಡ, Southeast Asian Indonesian, Vietnamese, Thai, မြန်မာဘာသာ, বাংলা
European español, Deutsch, français, Greek, português do Brasil, polski, română, русский, Nederlands, norsk, svenska, suomi, Italian
Middle Eastern & African عربى, Turkish, Persian, Hebrew, Afrikaans, isiZulu, Kiswahili,
Other Bulgarian, Hungarian, Czech, Swedish, മലയാളം, मराठी, ਪੰਜਾਬੀ, ગુજરાતી, Portuguese, Ukrainian