AC-927

AC-927‏‎ is a synthetic compound that belongs to the class of organic compounds known as benzodiazepines. It is primarily used in the field of pharmacology for research purposes.

Chemical Structure

AC-927‏‎ is a benzodiazepine derivative, which means it is structurally related to benzodiazepines, a class of drugs that includes medications like diazepam and alprazolam. The chemical structure of AC-927‏‎ includes a benzene ring fused to a seven-membered diazepine ring.

Pharmacological Activity

AC-927‏‎ is known for its agonist activity at the peroxisome proliferator-activated receptor alpha (PPARα), a type of nuclear receptor that plays a crucial role in the regulation of lipid metabolism and inflammation. By activating PPARα, AC-927‏‎ can potentially influence these biological processes.

Research Applications

Due to its pharmacological activity, AC-927‏‎ is used in research to study the role of PPARα in various biological processes and diseases. For example, it can be used to investigate the role of PPARα in atherosclerosis, a disease characterized by the buildup of fats, cholesterol, and other substances in and on the artery walls.

Safety and Toxicity

As with all synthetic compounds, the safety and toxicity of AC-927‏‎ are important considerations. While specific data on AC-927‏‎ may not be readily available, benzodiazepines in general can cause side effects such as drowsiness, dizziness, and dependence with long-term use. Therefore, AC-927‏‎ should be handled with care in a research setting.

See Also

• Benzodiazepine
• Peroxisome proliferator-activated receptor alpha
• Atherosclerosis