Accelerated phase chronic myelogenous leukemia
From WikiMD's WELLNESSPEDIA
| Accelerated phase chronic myelogenous leukemia | |
|---|---|
| Synonyms | Accelerated phase CML |
| Pronounce | N/A |
| Specialty | N/A |
| Symptoms | Fatigue (medical), fever, weight loss, splenomegaly, bone pain |
| Complications | Blast crisis, anemia, thrombocytopenia |
| Onset | Typically in middle age |
| Duration | Chronic, with progression |
| Types | N/A |
| Causes | Philadelphia chromosome (BCR-ABL1 fusion gene) |
| Risks | Radiation exposure, genetic predisposition |
| Diagnosis | Complete blood count, bone marrow biopsy, cytogenetic analysis |
| Differential diagnosis | Chronic myelogenous leukemia, acute myeloid leukemia, myelodysplastic syndrome |
| Prevention | N/A |
| Treatment | Tyrosine kinase inhibitors, chemotherapy, hematopoietic stem cell transplantation |
| Medication | N/A |
| Prognosis | Variable, depends on response to treatment |
| Frequency | Rare, as a phase of chronic myelogenous leukemia |
| Deaths | N/A |
a phase of chronic myelogenous leukemia characterized by one or more of the following
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